Mini Transmitter Saves Babies
A NASA-DEVELOPED "PILL TRANSMITTER"
IS expected to begin monitoring mothers and their babies following
corrective fetal surgery for body temperature, pressure and other
vital signs in the womb and then radioing physicians this critical
information. An even smaller pill that can be swallowed by astronauts
to track vital signs during space travel will be developed later.
Ames Research Center, Moffett Field, California, developed the
pill in cooperation with the Fetal Treatment Center at the University
of California at San Francisco. "If you implant our pill, doctors
are able to monitor the magnitude and frequency of contractions
to enable physicians to identify the onset of preterm labor early
enough to prevent it from becoming life threatening to the fetus,"
said Dr. Carsten Mundt, an electrical engineer on the Sensors 2000!
team at Ames.
Mundt also said preterm labor is difficult to predict and monitor
with conventional equipment. Nearly every fetal surgery results
in preterm labor that, if left untreated, can lead to the baby's
death, according to Mundt.
The surgeons at the University of California at San Francisco
have recently begun using an endoscopic technique for these corrective
surgeries to minimize the risk of inducing preterm labor. In this
technique, small incisions are made, and tube-like devices called
endoscopes are inserted through the mother's abdominal wall. Prior
to this technique, pediatric surgeons at the Fetal Treatment Center
pioneered a cesarean surgical approach to implant a larger sensor-transmitter
for monitoring mothers and fetuses. In 1981, Michael Harrison, M.D.,
the Fetal Treatment Center's founding director, performed the world's
first corrective fetal surgery.
The pill, about one-third of an inch across and one and a third
inches long, was developed because sensor-transmitters small enough
to fit through the endoscopic surgery tubes were not commercially
available. For ulcer patients, pills could monitor intestinal pressure
changes and stomach acidity. Smaller pills, currently in development,
will transmit fetal heart data and measurements for fetal body chemicals,
including ionic calcium, carbon dioxide and glucose, according to
Sensors 2000! scientist Dr. Chris Somps at Ames.
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| This pill-shaped transmitter,
with other versions in development, passes through endoscopic
tubes to radio critical information to physicians from mothers
and their babies following corrective fetal surgery.
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"We would also like to use this technology to study what happens
to astronauts during space travel," said Ames team member Mike Skidmore.
"Not only could they swallow the smaller pill transmitters we plan
to develop, but we have a conceptual design of small, flat transmitters
that can be taped to the body like plastic bandages."
There are many possible medical uses for this technology. A prototype
version of another pill to measure and transmit pH, or acidity,
in the fetus is being tested by Ames scientists.
For more information, contact Mike Skidmore, Deputy Manager, Sensors
2000! Program, at Ames Research Center.
Call: 650/604-6069, Fax: 650/961-8472, E-mail: mskidmore@mail.arc.nasa.gov
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MICROGRAVITY
RESEARCH GRANTS ANNOUNCED
The
majority of research supported under microgravity biotechnology
research grants recently announced by NASA includes 34 new
research efforts and continuation of work currently funded
by NASA. The protein crystallization, cell science studies
and new technology development may affect areas in structure-based
drug design, tissue engineering and biosensor development.
NASA
has selected 48 researchers to receive grants to conduct microgravity
biotechnology research. Sponsored by NASA's Office of Life
and Microgravity Sciences and Applications, this research
allows investigators to take advantage of a low-gravity environment
to improve understanding of fundamental physical and chemical
processes associated with biotechnology. Of these grants,
40 are to conduct ground-based research, while the remaining
8 are flight definition efforts. The investigators will have
NASA's microgravity research facilities at their disposal,
such as aircraft flying parabolic trajectories and sounding
rockets. The flight definition investigators will work toward
experiments on the International Space Station.
NASA
received 165 proposals that were peer-reviewed by scientific
and technical experts from academia, government and industry.
In addition, those proposals selected for flight definition
were reviewed in terms of engineering feasibility by a team
from NASA's Marshall Space Flight Center in Huntsville, Alabama.
A list of awardees can be found at: ftp://ftp.hq.nasa.gov/pub/pao/pressrel/
1998/98-217a.txt
For more
information, contact Renee N. Juhans at NASA Headquarters.
Call: 202/358-1712,
Fax: 202/358-4210,
E-mail: rjuhans@hq.nasa.gov
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